Thermoanalytical studies of carbamazepine: hydration/dehydration, thermal decomposition, and solid phase transitions

• Main Authors: Mônia Aparecida Lemos Pinto (Author), Beatriz Ambrozini (Author), Ana Paula Garcia Ferreira (Author), Éder Tadeu Gomes Cavalheiro (Author)
• Format: Book
• Published: Universidade de São Paulo, 2014-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Carbamazepine (CBZ), a widely used anticonvulsant drug, can crystallize and exhibits four polymorphic forms and one dihydrate. Anhydrous CBZ can spontaneously absorb water and convert to the hydrate form whose different crystallinity leads to lower biological activity. The present study was concerne...