In vivo effects of bradykinin B2 receptor agonists with varying susceptibility to peptidases.

• Autores principales: Mélissa eJean (Autor), Lajos eGera (Autor), Xavier eCharest-Morin (Autor), François eMarceau (Autor), Hélène eBachelard (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2016-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

We reported evidence of bradykinin (BK) regeneration from C-terminal extended BK sequences that behave as peptidase-activated B2 receptor (B2R) agonists. Further to these in vitro studies, we carried out in vivo experiments to verify hemodynamic effects of BK analogs exhibiting variable susceptibili...