Pharmacokinetics, bioavailability, metabolism and excretion of δ-viniferin in rats

• Main Authors: Ping Mao (Author), Yinping Lei (Author), Tingting Zhang (Author), Chen Ma (Author), Bo Jin (Author), Tong Li (Author)
• Format: Book
• Published: Elsevier, 2016-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A highly rapid and sensitive liquid chromatographic-electrospray ionization tandem mass spectrometric (LC-ESI-MS/MS) method was developed and validated for the determination of trans-δ-viniferin (Rs-1) in rat plasma, urine and feces. All biological samples were prepared by liquid-liquid extraction a...