Ebselen Interferes with Alzheimer's Disease by Regulating Mitochondrial Function

• Main Authors: Xuexia Li (Author), Qingqing Shi (Author), Hao Xu (Author), Yufang Xiong (Author), Chao Wang (Author), Linfeng Le (Author), Junliang Lian (Author), Guoli Wu (Author), Feiyuan Peng (Author), Qiong Liu (Author), Xiubo Du (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

(1) Background: With unknown causes and no effective treatment available, Alzheimer's disease (AD) places enormous pressure on families and society. Our previous study had shown that Ebselen at a high concentration (10.94 μM) improved the cognition of triple-transgenic AD (3×Tg-AD) mice and all...