Wogonin upregulates SOCS3 to alleviate the injury in Diabetic Nephropathy by inhibiting TLR4-mediated JAK/STAT/AIM2 signaling pathway

• 主要な著者: Yufeng Liu (著者), Mengbi Zhang (著者), Lu Zeng (著者), Yanhong Lai (著者), Songzhao Wu (著者), Xiaoyan Su (著者)
• フォーマット: 図書
• 出版事項: BMC, 2024-06-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Background Diabetic nephropathy (DN) is a life-threatening renal disease and needs urgent therapies. Wogonin is renoprotective in DN. This study aimed to explore the mechanism of how wogonin regulated high glucose (HG)-induced renal cell injury. Methods Diabetic mice (db/db), control db/m m...