Induction of CD14 Expression and Differentiation to Monocytes or Mature Macrophages in Promyelocytic Cell Lines: New Approach

• Main Authors: Fatemeh Zamani (Author), Fatemeh Zare Shahneh (Author), Leili Aghebati-Maleki (Author), Behzad Baradaran (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2013-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: CD14, one of the main differentiation markers on the surface of myeloid lineage cells, acts as a key role in activation of LPS-induced monocytes. LPS (lipopolysaccharide) binds to LPS-binding protein in plasma and are delivered to the cell surface receptor CD14. In this study, Various stimu...