Study on the cellular internalization mechanisms and in vivo anti-bone metastasis prostate cancer efficiency of the peptide T7-modified polypeptide nanoparticles

• Main Authors: Yongwei Gu (Author), Xinmei Chen (Author), Haiyan Zhang (Author), Heyi Wang (Author), Hang Chen (Author), Sifan Huang (Author), Youfa Xu (Author), Yuansheng Zhang (Author), Xin Wu (Author), Jianming Chen (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bone-metastasis prostate cancer (BMPCa)-targeting gene therapy is gaining increasing concern in recent years. The peptide T7-modified polypeptide nanoparticles for delivery DNA (CRD-PEG-T7/pPMEPA1) was prepared as our previous study. However, the feasibility of CRD-PEG-T7/pPMEPA1 for BMPCa treatment...