Combination of levetiracetam with sodium selenite prevents pentylenetetrazole-induced kindling and behavioral comorbidities in rats

• Main Authors: Zohabia Rehman (Author), Talha Farooq (Author), Sana Javaid (Author), Waseem Ashraf (Author), Muhammad Fawad Rasool (Author), Noreen Samad (Author), Maryam Tariq (Author), Syed Muhammad Muneeb Anjum (Author), Farzane Sivandzade (Author), Faisal Alotaibi (Author), Faleh Alqahtani (Author), Imran Imran (Author)
• Format: Book
• Published: Elsevier, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: The pentylenetetrazol (PTZ)-induced kindling model acts through the antagonism of central GABAA receptors and is one of the most widely used experimental animal models to study the characteristics of seizure development, behavioral manifestations and evaluation of antiseizure effects o...