FGF21 regulates insulin sensitivity following long-term chronic stress

• Main Authors: Tomas Jelenik (Author), Matthias Dille (Author), Sabrina Müller-Lühlhoff (Author), Dhiraj G. Kabra (Author), Zhou Zhou (Author), Christian Binsch (Author), Sonja Hartwig (Author), Stefan Lehr (Author), Alexandra Chadt (Author), Eva M.J. Peters (Author), Johannes Kruse (Author), Michael Roden (Author), Hadi Al-Hasani (Author), Tamara R. Castañeda (Author)
• Format: Book
• Published: Elsevier, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Post-traumatic stress disorder (PTSD) increases type 2 diabetes risk, yet the underlying mechanisms are unclear. We investigated how early-life exposure to chronic stress affects long-term insulin sensitivity. Methods: C57Bl/6J mice were exposed to chronic variable stress for 15 days (Cvs...