Functional transcriptomics of wild-caught Lutzomyia intermedia salivary glands: identification of a protective salivary protein against Leishmania braziliensis infection.

• Main Authors: Tatiana R de Moura (Author), Fabiano Oliveira (Author), Marcia W Carneiro (Author), José Carlos Miranda (Author), Jorge Clarêncio (Author), Manoel Barral-Netto (Author), Cláudia Brodskyn (Author), Aldina Barral (Author), José M C Ribeiro (Author), Jesus G Valenzuela (Author), Camila I de Oliveira (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Leishmania parasites are transmitted in the presence of sand fly saliva. Together with the parasite, the sand fly injects salivary components that change the environment at the feeding site. Mice immunized with Phlebotomus papatasi salivary gland (SG) homogenate are protected against Lei...