Deep Sequence Analysis of AgoshRNA Processing Reveals 3' A Addition and Trimming

• Main Authors: Alex Harwig (Author), Elena Herrera-Carrillo (Author), Aldo Jongejan (Author), Antonius Hubertus van Kampen (Author), Ben Berkhout (Author)
• Format: Book
• Published: Elsevier, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The RNA interference (RNAi) pathway, in which microprocessor and Dicer collaborate to process microRNAs (miRNA), was recently expanded by the description of alternative processing routes. In one of these noncanonical pathways, Dicer action is replaced by the Argonaute2 (Ago2) slicer function. It was...