pH-Sensitive In Situ Gel of Mirtazapine Invasomes for Rectal Drug Delivery: Protruded Bioavailability and Anti-Depressant Efficacy

• Main Authors: Essam M. Eissa (Author), Amani M. El Sisi (Author), Marina A. Bekhet (Author), Fatma I. Abo El-Ela (Author), Rasha M. Kharshoum (Author), Adel A. Ali (Author), Majed Alrobaian (Author), Ahmed M. Abdelhaleem Ali (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present research emphasizes fabrication alongside the assessment of an innovative nano-vesicular membranous system known as invasomes (NVMs) laden with Mirtazapine for rectal administration. This system could circumvent the confines of orally administered counterparts regarding dose schedules an...