BRD4 promotes gouty arthritis through MDM2-mediated PPARγ degradation and pyroptosis

Abstract Background Gouty arthritis (GA) is characterized by monosodium urate (MSU) crystal accumulation that instigates NLRP3-mediated pyroptosis; however, the underlying regulatory mechanisms have yet to be fully elucidated. The present research endeavors to elucidate the regulatory mechanisms und...

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Main Authors: Xiaoxia Xu (Author), Hongbin Qiu (Author)
Format: Book
Published: BMC, 2024-05-01T00:00:00Z.
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3rd Floor Main Library

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