Application of the Nested Enzyme‐Within‐Enterocyte (NEWE) Turnover Model for Predicting the Time Course of Pharmacodynamic Effects
The gut wall consists of many biological elements, including enterocytes. Rapid turnover, a prominent feature of the enterocytes, has generally been ignored in the development of enterocyte‐targeting drugs, although it has a comparable rate to other kinetic rates. Here, we investigated the impact of...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
Wiley,
2020-11-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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