DNA binding of ethyl 2-substituted aminothiazole-4-carboxylate analogues: A molecular modeling approach to predict their antitumor activity
The synthesis and the antitumor potential of 2-substituted aminothiazole-4-carboxylate, structurally-related to the antitumor antibiotic netropsin (NT) were reported. However, the exact mode of action and SAR of these compounds remained undefined. Currently, an energy-based molecular modeling approa...
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| Үндсэн зохиолчид: | , |
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| Формат: | Ном |
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SpringerOpen,
2015-06-01T00:00:00Z.
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A1234.567 |
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| Хуулбар 1 | Бэлэн |