DNA binding of ethyl 2-substituted aminothiazole-4-carboxylate analogues: A molecular modeling approach to predict their antitumor activity

The synthesis and the antitumor potential of 2-substituted aminothiazole-4-carboxylate, structurally-related to the antitumor antibiotic netropsin (NT) were reported. However, the exact mode of action and SAR of these compounds remained undefined. Currently, an energy-based molecular modeling approa...

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Main Authors: Laila A. Abouzeid (Author), Hussein I. El-Subbagh (Author)
Format: Book
Published: SpringerOpen, 2015-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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