The Distinct Roles of Calmodulin and Calmodulin Kinase II in the Reversal of Run-Down of L-Type Ca2+ Channels in Guinea-Pig Ventricular Myocytes

• Asıl Yazarlar: Li-Ying Hao (Yazar), Wu-Yang Wang (Yazar), Etsuko Minobe (Yazar), Dong-Yun Han (Yazar), Jian-Jun Xu (Yazar), Asako Kameyama (Yazar), Masaki Kameyama (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2009-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

In this study, we investigated the roles of calmodulin kinase II (CaMKII) and calmodulin (CaM) in the reversal of run-down of L-type Ca2+ channels. Single Ca2+-channel activities in guinea-pig ventricular myocytes were recorded using the patch-clamp technique, and run-down of the channel activities...