Deletion of myeloid IRS2 enhances adipose tissue sympathetic nerve function and limits obesity

• Main Authors: Marie-Therese Rached (Author), Steven J. Millership (Author), Silvia M.A. Pedroni (Author), Agharul I. Choudhury (Author), Ana S.H. Costa (Author), Darran G. Hardy (Author), Justyna A. Glegola (Author), Elaine E. Irvine (Author), Colin Selman (Author), Megan C. Woodberry (Author), Vijay K. Yadav (Author), Sanjay Khadayate (Author), Antonio Vidal-Puig (Author), Samuel Virtue (Author), Christian Frezza (Author), Dominic J. Withers (Author)
• Format: Book
• Published: Elsevier, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Sympathetic nervous system and immune cell interactions play key roles in the regulation of metabolism. For example, recent convergent studies have shown that macrophages regulate obesity through brown adipose tissue (BAT) activation and beiging of white adipose tissue (WAT) via effects u...