Acute Chagas disease induces cerebral microvasculopathy in mice.

• Main Authors: Lindice Mitie Nisimura (Author), Vanessa Estato (Author), Elen Mello de Souza (Author), Patricia A Reis (Author), Marcos Adriano Lessa (Author), Hugo Caire Castro- (Author), Mirian Claudia de Souza Pereira (Author), Eduardo Tibiriçá (Author), Luciana Ribeiro Garzoni (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cardiomyopathy is the main clinical form of Chagas disease (CD); however, cerebral manifestations, such as meningoencephalitis, ischemic stroke and cognitive impairment, can also occur. The aim of the present study was to investigate functional microvascular alterations and oxidative stress in the b...