Leishmania metacyclogenesis is promoted in the absence of purines.

• Main Authors: Tiago Donatelli Serafim (Author), Amanda Braga Figueiredo (Author), Pedro Augusto Carvalho Costa (Author), Eduardo Almeida Marques- (Author), Ricardo Gonçalves (Author), Sandra Aparecida Lima de Moura (Author), Nelder Figueiredo Gontijo (Author), Sydnei Magno da Silva (Author), Marilene Suzan Marques Michalick (Author), José Roberto Meyer-Fernandes (Author), Roberto Paes de Carvalho (Author), Silvia Reni Bortolin Uliana (Author), Juliana Lopes Rangel Fietto (Author), Luís Carlos Crocco Afonso (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leishmania parasites, the causative agent of leishmaniasis, are transmitted through the bite of an infected sand fly. Leishmania parasites present two basic forms known as promastigote and amastigote which, respectively, parasitizes the vector and the mammalian hosts. Infection of the vertebrate hos...