Engineered and construction of pDS132::∆virG as suicide vector for targeted gene deletion of virG from Shigella flexneri 2a in order to generation a live attenuated Shigella vaccine

• Autori principali: Mojtaba Saadati (Autore), Sayed Mostafa Hosseini (Autore)
• Natura: Libro
• Pubblicazione: Fasa University of Medical Sciences, 2011-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Background & Objective: Shigella are Gram negative bacteria capable of inducing their entry into non-phagocytic cells via secretion of various effector proteins called invasion plasmid antigens (Ipas). The most important of them is VirG protein. Live attenuated Shigella vaccines have indicated p...