PON1 and PON3 in Alzheimer's Disease: Similar Functions but Different Roles

• Principais autores: Alessandro Trentini (Autor), Valentina Rosta (Autor), Raffaella Riccetti (Autor), Gianmarco Mola (Autor), Riccardo Galletti (Autor), Marco Pinotti (Autor), Vincenza Senia (Autor), Giovanni Zuliani (Autor), Carlo Cervellati (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2024-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Paraoxonase 1 (PON1) and Paraoxonase 3 (PON3) are enzymes located on the surface of high-density lipoprotein (HDL) and share similar antioxidant properties, possibly modulated by other proteins such as Myeloperoxidase (MPO), which drives the shift from functional to dysfunctional HDL. PON1 has been...