Muscle‐restricted nuclear receptor interaction protein knockout causes motor neuron degeneration through down‐regulation of myogenin at the neuromuscular junction

• Главные авторы: Hsin‐Hsiung Chen (Автор), Li‐Kai Tsai (Автор), Kuan‐Yu Liao (Автор), Tung‐Chien Wu (Автор), Yun‐Hsin Huang (Автор), Yuan‐Chun Huang (Автор), Szu‐Wei Chang (Автор), Pei‐Yu Wang (Автор), Yeou‐Ping Tsao (Автор), Show‐Li Chen (Автор)
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• Опубликовано: Wiley, 2018-08-01T00:00:00Z.
• Предметы: article
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Abstract Background Nuclear receptor interaction protein (NRIP) is a calcium/calmodulin (CaM) binding protein. Nuclear receptor interaction protein interacts with CaM to activate calcineurin and CaMKII signalling. The conventional NRIP knockout mice (global knockout) showed muscular abnormality with...