Cellular photo(geno)toxicity of gefitinib after biotransformation
Gefitinib (GFT) is a selective epidermal growth factor receptor (EGFR) inhibitor clinically used for the treatment of patients with non-small cell lung cancer. Bioactivation by mainly Phase I hepatic metabolism leads to chemically reactive metabolites such as O-Demethyl gefitinib (DMT-GFT), 4-Defluo...
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| Main Authors: | , , , , |
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| Format: | Book |
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Frontiers Media S.A.,
2023-06-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |