Inflammation, HIF-1, and the Epigenetics That Follows

• Główni autorzy: Claudio Brigati (Autor), Barbara Banelli (Autor), Angela di Vinci (Autor), Ida Casciano (Autor), Giorgio Allemanni (Autor), Alessandra Forlani (Autor), Luana Borzì (Autor), Massimo Romani (Autor)
• Format: Książka
• Wydane: Hindawi Limited, 2010-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

We summarize recent findings linking inflammatory hypoxia to chromatin modifications, in particular to repressive histone signatures. We focus on the role of Hypoxia-Induced Factor-1 in promoting the activity of specific histone demethylases thus deeply modifying chromatin configuration. The consequ...