Genetic and epigenetic mechanisms influencing acute to chronic postsurgical pain transitions in pediatrics: Preclinical to clinical evidence

• Main Authors: Adam. J. Dourson (Author), Adam. Willits (Author), Namrata.G.R. Raut (Author), Leena Kader (Author), Erin Young (Author), Michael.P. Jankowski (Author), Vidya Chidambaran (Author)
• Formato: Livro
• Publicado em: Taylor & Francis Group, 2021-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background Chronic postsurgical pain (CPSP) in children remains an important problem with no effective preventive or therapeutic strategies. Recently, genomic underpinnings explaining additional interindividual risk beyond psychological factors have been proposed. Aims We present a comprehensive rev...