A Combinatorial Cell and Drug Delivery Strategy for Huntington's Disease Using Pharmacologically Active Microcarriers and RNAi Neuronally-Committed Mesenchymal Stromal Cells

For Huntington’s disease (HD) cell-based therapy, the transplanted cells are required to be committed to a neuronal cell lineage, survive and maintain this phenotype to ensure their safe transplantation in the brain. We first investigated the role of RE-1 silencing transcription factor (REST) inhibi...

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Bibliographic Details
Main Authors: Emilie M. André (Author), Gaëtan J. Delcroix (Author), Saikrishna Kandalam (Author), Laurence Sindji (Author), Claudia N. Montero-Menei (Author)
Format: Book
Published: MDPI AG, 2019-10-01T00:00:00Z.
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3rd Floor Main Library

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