Glutathione S-conjugates as prodrugs to target drug-resistant tumors
Living organisms are continuously exposed to xenobiotics. The major phase of enzymatic detoxification in many species is the conjugation of activated xenobiotics to reduced glutathione (GSH) catalyzed by the glutathione-S-transferase (GST). It has been reported that some compounds, once transformed...
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Frontiers Media S.A.,
2014-08-01T00:00:00Z.
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