Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen

• Main Authors: Brambilla Donald (Author), Clair Betsy (Author), McKie Virgil C (Author), Snieder Harold (Author), Adams Gaye T (Author), Adams Robert J (Author), Kutlar Ferdane (Author), Kutlar Abdullah (Author)
• Format: Book
• Published: BMC, 2003-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The phenotypic heterogeneity of sickle cell disease is likely the result of multiple genetic factors and their interaction with the sickle mutation. High transcranial doppler (TCD) velocities define a subgroup of children with sickle...