Testis cell pyroptosis mediated by CASP1 and CASP4: possible sertoli cell-only syndrome pathogenesis

• Main Authors: Wantao Liu (Author), Xinan Li (Author), Qiang Ma (Author), Yongtong Zhu (Author), Wenzhong Zhao (Author), Yisheng Yang (Author), Weiqiang Xiao (Author), Daxiong Huang (Author), Fengbo Cai (Author), David Yiu Leung Chan (Author), Shanchao Zhao (Author), Qingjun Chu (Author)
• Format: Book
• Published: BMC, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Sertoli cell-only syndrome (SCOS) is the most serious pathological type of non-obstructive azoospermia. Recently, several genes related to SCOS have been identified, including FANCM, TEX14, NR5A1, NANOS2, PLK4, WNK3, and FANCA, but they cannot fully explain the pathogenesis of SC...