Stability investigations of cytochrome P450 (CYP) enzymes immediately after death in a pig model support the applicability of postmortem hepatic CYP quantification

Abstract Quantification of drug‐metabolizing cytochrome P450 (CYP) isoforms using LC-MS/MS has been proposed as a potential way of estimating antemortem CYP levels using postmortem tissue, but the postmortem stability of CYP proteins is incompletely investigated. If one can use data obtained from th...

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Main Authors: Kata W. Pedersen (Author), Jakob Hansen (Author), Jørgen B. Hasselstrøm (Author), Jakob R. Jornil (Author)
Format: Book
Published: Wiley, 2021-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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