Synthesis, Computational Study, and In Vitro α-Glucosidase Inhibitory Action of 1,3,4-Thiadiazole Derivatives of 3-Aminopyridin-2(1<i>H</i>)-ones

• Päätekijät: Zarina Shulgau (Tekijä), Irina V. Palamarchuk (Tekijä), Shynggys Sergazy (Tekijä), Assel Urazbayeva (Tekijä), Yerlan Ramankulov (Tekijä), Ivan V. Kulakov (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2024-03-01T00:00:00Z.
• Aiheet: article
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This article reports on the synthesis of nine promising new 1,3,4-thiadiazole derivatives based on 3-aminopyridones, containing various acidic linkers. The synthesis was carried out by cyclizing the corresponding thiohydrazides <b>4a</b>-<b>c</b> and anhydrides of glutaric, m...