The effects of agomelatine in cisplatin-induced toxicity on the kidney and liver tissues: In vivo study

• Main Authors: Fatma Nihan Cankara (Author), Caner Günaydın (Author), Zülfinaz Betül Çelik (Author), Yasemin Şahin (Author), Şakir Pekgöz (Author), Yalçın Erzurumlu (Author), Kanat Gülle (Author)
• Format: Book
• Published: Universidade de São Paulo, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Nephrotoxicity and hepatotoxicity are frequently seen adverse effects during cisplatin chemotherapy. In this study, we investigated the effects of agomelatine on cisplatin-induced toxicity in the kidney and liver. Animals were administered with a single dose of cisplatin (7 mg/kg, i.p.) and...