Polydatin Glycosides Improve Monocrotaline-Induced Pulmonary Hypertension Injury by Inhibiting Endothelial-To-Mesenchymal Transition

• Glavni autori: Xing Chen (Autor), Yao He (Autor), Zhijie Yu (Autor), Jianli Zuo (Autor), Yan Huang (Autor), Yi Ruan (Autor), Xiaoyuan Zheng (Autor), Yu Ma (Autor)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Objective: To study the effect of polydatin on the injury of pulmonary arterial hypertension (PAH) induced by monocrotaline (MCT).Methods: SD rats were induced to develop PAH injury by a single subcutaneous injection of MCT (60 mg/kg). From the second day, rats in the administration group were orall...