Production, purification, and radiolabeling of the 203Pb/212Pb theranostic pair

• Main Authors: Brooke L. McNeil (Author), Andrew K. H. Robertson (Author), Winnie Fu (Author), Hua Yang (Author), Cornelia Hoehr (Author), Caterina F. Ramogida (Author), Paul Schaffer (Author)
• Formato: Livro
• Publicado em: SpringerOpen, 2021-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Lead-212 (212Pb, t1/2 = 10.6 h) and lead-203 (203Pb, t1/2 = 51.9 h) are an element-equivalent, or a matched theranostic radioisotope pair that show great potential for application in targeted radionuclide therapy (TRT) and single-photon emission computed tomography (SPECT), respe...