From Antarctica to cancer research: a novel human DNA topoisomerase 1B inhibitor from Antarctic sponge Dendrilla antarctica

• Asıl Yazarlar: Alessio Ottaviani (Yazar), Joshua Welsch (Yazar), Keli Agama (Yazar), Yves Pommier (Yazar), Alessandro Desideri (Yazar), Bill J. Baker (Yazar), Paola Fiorani (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Nature has been always a great source of possible lead compounds to develop new drugs against several diseases. Here we report the identification of a natural compound, membranoid G, derived from the Antarctic sponge Dendrilla antarctica displaying an in vitro inhibitory activity against human DNA t...