Synthesis of Functionalized <i>N</i>-(4-Bromophenyl)furan-2-carboxamides via Suzuki-Miyaura Cross-Coupling: Anti-Bacterial Activities against Clinically Isolated Drug Resistant <i>A. baumannii</i>, <i>K. pneumoniae</i>, <i>E. cloacae</i> and MRSA and Its Validation via a Computational Approach

• Main Authors: Ayesha Siddiqa (Author), Muhammad Zubair (Author), Muhammad Bilal (Author), Nasir Rasool (Author), Muhammad Usman Qamar (Author), Aqsa Khalid (Author), Gulraiz Ahmad (Author), Muhammad Imran (Author), Sajid Mahmood (Author), Ghulam Abbas Ashraf (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<i>N</i>-(4-bromophenyl)furan-2-carboxamide (<b>3</b>) was synthesized by the reaction furan-2-carbonyl chloride (<b>1</b>) and 4-bromoaniline (<b>2</b>) in the presence of Et₃N in excellent yields of 94%. The carboxamide (<b&...