Developing Robust Human Liver Microsomal Stability Prediction Models: Leveraging Inter-Species Correlation with Rat Data

<b>Objectives:</b> Pharmacokinetic issues were the leading cause of drug attrition, accounting for approximately 40% of all cases before the turn of the century. To this end, several high-throughput in vitro assays like microsomal stability have been developed to evaluate the pharmacokin...

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Main Authors: Pranav Shah (Author), Vishal B. Siramshetty (Author), Ewy Mathé (Author), Xin Xu (Author)
Format: Book
Published: MDPI AG, 2024-09-01T00:00:00Z.
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3rd Floor Main Library

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