L-cysteine methyl ester overcomes the deleterious effects of morphine on ventilatory parameters and arterial blood-gas chemistry in unanesthetized rats

• প্রধান লেখক: Paulina M. Getsy (লেখক), Santhosh M. Baby (লেখক), Walter J. May (লেখক), James N. Bates (লেখক), Christopher R. Ellis (লেখক), Michael G. Feasel (লেখক), Christopher G. Wilson (লেখক), Tristan H. J. Lewis (লেখক), Benjamin Gaston (লেখক), Yee-Hsee Hsieh (লেখক), Stephen J. Lewis (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

We are developing a series of thiolesters that produce an immediate and sustained reversal of the deleterious effects of opioids, such as morphine and fentanyl, on ventilation without diminishing the antinociceptive effects of these opioids. We report here the effects of systemic injections of L-cys...