FASTAptamer: A Bioinformatic Toolkit for High-throughput Sequence Analysis of Combinatorial Selections

• मुख्य लेखकों: Khalid K Alam (लेखक), Jonathan L Chang (लेखक), Donald H Burke (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2015-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

High-throughput sequence (HTS) analysis of combinatorial selection populations accelerates lead discovery and optimization and offers dynamic insight into selection processes. An underlying principle is that selection enriches high-fitness sequences as a fraction of the population, whereas low-fitne...