Protein kinase C and extracellular signal-regulated kinase regulate movement, attachment, pairing and egg release in Schistosoma mansoni.

• Main Authors: Margarida Ressurreição (Author), Paulu De Saram (Author), Ruth S Kirk (Author), David Rollinson (Author), Aidan M Emery (Author), Nigel M Page (Author), Angela J Davies (Author), Anthony J Walker (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Protein kinases C (PKCs) and extracellular signal-regulated kinases (ERKs) are evolutionary conserved cell signalling enzymes that coordinate cell function. Here we have employed biochemical approaches using 'smart' antibodies and functional screening to unravel the importance of these enz...