Bio-Oriented Synthesis and Molecular Docking Studies of 1,2,4-Triazole Based Derivatives as Potential Anti-Cancer Agents against HepG2 Cell Line

• Main Authors: Naheed Akhter (Author), Sidra Batool (Author), Samreen Gul Khan (Author), Nasir Rasool (Author), Fozia Anjum (Author), Azhar Rasul (Author), Şevki Adem (Author), Sadaf Mahmood (Author), Aziz ur Rehman (Author), Mehr un Nisa (Author), Zainib Razzaq (Author), Jørn B. Christensen (Author), Mohammed A. S. Abourehab (Author), Syed Adnan Ali Shah (Author), Syahrul Imran (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Triazole-based acetamides serve as important scaffolds for various pharmacologically active drugs. In the present work, structural hybrids of 1,2,4-triazole and acetamides were furnished by chemically modifying 2-(4-isobutylphenyl) propanoic acid (<b>1</b>). Target compounds <b>7a-...