Herbal formula Huangqi Guizhi Wuwu decoction attenuates paclitaxel-related neurotoxicity via inhibition of inflammation and oxidative stress

• Main Authors: Zhangming Lv (Author), Jiayun Shen (Author), Xuejiao Gao (Author), Yonglan Ruan (Author), Jinying Ling (Author), Rongwei Sun (Author), Jingya Dai (Author), Haizhen Fan (Author), Xiaolan Cheng (Author), Peng Cao (Author)
• Format: Book
• Published: BMC, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Paclitaxel-induced peripheral neuropathy (PIPN) is a challenging clinical problem during chemotherapy. Our previous work found that herbal formula Huangqi Guizhi Wuwu decoction (HGWD) could reduce oxaliplatin-induced neurotoxicity. However, its effect on PIPN remains unknown. In...