Physical activity unveils the relationship between mitochondrial energetics, muscle quality, and physical function in older adults

• Main Authors: Giovanna Distefano (Author), Robert A. Standley (Author), Xiaolei Zhang (Author), Elvis A. Carnero (Author), Fanchao Yi (Author), Heather H. Cornnell (Author), Paul M. Coen (Author)
• Format: Book
• Published: Wiley, 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The concept of mitochondrial dysfunction in ageing muscle is highly controversial. In addition, emerging evidence suggests that reduced muscle oxidative capacity and efficiency underlie the aetiology of mobility loss in older adults. Here, we hypothesized that studying well‐pheno...