Apomorphine Suppresses the Progression of Steatohepatitis by Inhibiting Ferroptosis

• Main Authors: Hiroshi Maeda (Author), Kouichi Miura (Author), Kenichi Aizawa (Author), Oyunjargal Bat-Erdene (Author), Miho Sashikawa-Kimura (Author), Eri Noguchi (Author), Masako Watanabe (Author), Naoya Yamada (Author), Hitoshi Osaka (Author), Naoki Morimoto (Author), Hironori Yamamoto (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The role of ferroptosis in steatohepatitis development is largely unknown. We investigated (1) whether hepatocyte ferroptosis occurs in a gene-modified steatohepatitis model without modifying dietary components, (2) whether ferroptosis occurs at an early stage of steatohepatitis, and (3) whether apo...