The role of cGAS in epithelial dysregulation in inflammatory bowel disease and gastrointestinal malignancies

• Egile Nagusiak: Anna Ramos (Egilea), Nazih Bizri (Egilea), Elizabeth Novak (Egilea), Kevin Mollen (Egilea), Sidrah Khan (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The gastrointestinal tract is lined by an epithelial monolayer responsible for selective permeability and absorption, as well as protection against harmful luminal contents. Recognition of foreign or aberrant DNA within these epithelial cells is, in part, regulated by pattern recognition receptors s...