Preparation of Co-Amorphous Systems by Freeze-Drying

• मुख्य लेखकों: Melvin Wostry (लेखक), Hanna Plappert (लेखक), Holger Grohganz (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2020-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Freeze-drying was evaluated as a production technique for co-amorphous systems of a poorly water-soluble drug. Naproxen was freeze-dried together with arginine and lysine as co-former. To increase the solubility of naproxen in the starting solution, the applicability of five surfactants was investig...