Flow cytometry allows rapid detection of protein aggregates in cellular and zebrafish models of spinocerebellar ataxia 3

Flow cytometry allows rapid detection of protein aggregates in cellular and zebrafish models of spinocerebellar ataxia 3

Spinocerebellar ataxia 3 (SCA3, also known as Machado-Joseph disease) is a neurodegenerative disease caused by inheritance of a CAG repeat expansion within the ATXN3 gene, resulting in polyglutamine (polyQ) repeat expansion within the ataxin-3 protein. In this study, we have identified protein aggre...

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Main Authors: Katherine J. Robinson (Author), Madelaine C. Tym (Author), Alison Hogan (Author), Maxinne Watchon (Author), Kristy C. Yuan (Author), Stuart K. Plenderleith (Author), Emily K. Don (Author), Angela S. Laird (Author)
Format: Book
Published: The Company of Biologists, 2021-10-01T00:00:00Z.
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3rd Floor Main Library

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