miR-202-3p Regulates Sertoli Cell Proliferation, Synthesis Function, and Apoptosis by Targeting LRP6 and Cyclin D1 of Wnt/β-Catenin Signaling

• Main Authors: Chao Yang (Author), Chencheng Yao (Author), Ruhui Tian (Author), Zijue Zhu (Author), Liangyu Zhao (Author), Peng Li (Author), Huixing Chen (Author), Yuhua Huang (Author), Erlei Zhi (Author), Yuehua Gong (Author), Yunjing Xue (Author), Hong Wang (Author), Qingqing Yuan (Author), Zuping He (Author), Zheng Li (Author)
• Format: Book
• Published: Elsevier, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

MicroRNAs (miRNAs) play important roles in mammalian spermatogenesis, which is highly dependent on Sertoli cells. However, the functions and mechanisms of miRNAs in regulating human Sertoli cells remain largely unknown. Here, we report that hsa-miR-202-3p mediates the proliferation, apoptosis, and s...