Efficacy of stem cells on bone consolidation of distraction osteogenesis in animal models: a systematic review

• Main Authors: Carlos Manuel Rubio MORILLO (Author), Mariane Cristina SLONIAK (Author), Fernanda GONÇALVES (Author), Cristina Cunha VILLAR (Author)
• Format: Book
• Published: Sociedade Brasileira de Pesquisa Odontológica, 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Distraction osteogenesis (DO) relies on the recruitment and proliferation of mesenchymal stem cells (MSC) to the target site, where they differentiate into osteoblasts to promote bone formation. Nevertheless, MSC recruitment appears to be slow and limits bone formation in DO defects. Thus,...