Beneficial effect of prolonged heme oxygenase 1 activation in a rat model of chronic heart failure

• المؤلفون الرئيسيون: Massimo Collino (مؤلف), Alessandro Pini (مؤلف), Niccolò Mugelli (مؤلف), Rosanna Mastroianni (مؤلف), Daniele Bani (مؤلف), Roberto Fantozzi (مؤلف), Laura Papucci (مؤلف), Marilena Fazi (مؤلف), Emanuela Masini (مؤلف)
• التنسيق: كتاب
• منشور في: The Company of Biologists, 2013-07-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

SUMMARY We and others have previously demonstrated that heme oxygenase 1 (HO-1) induction by acute hemin administration exerts cardioprotective effects. Here, we developed a rat model of heart failure to investigate whether a long-term induction of HO-1 by chronic hemin administration exerted protec...